Chloroform and Gaslight Intoxication.

Chronic chloroform intoxication.

Chloroform was discovered in 1831 by a French chemist, Soubeiran, and independently by the American, Samuel Guthrie of Sachett's Harbour, in the State ofNew York (Duncum, 1947). Soubeiran obtained impure chloroform, which he provisionally called " bichloric ether ", by distilling a mixture of chloride of lime and alcohol. Liebig, in the following year, obtained a purer chloroform, which he name...

Prothrombin Deficiency and the Bleeding Tendency in Liver Injury (chloroform Intoxication)

The bleeding tendency in acute chloroform intoxication is due to deficiency in both plasma fibrinogen and plasma prothrombin. If the disorder is mild, no bleeding occurs. However, the prothrombin falls to rather low levels, although the fibrinogen falls only moderately. A bleeding tendency may also be produced by giving small repeated doses of chloroform. In such experiments, the hemorrhagic te...

Chloroform

It was perhaps fitting that Lieut.-Colonel Edward Lawrie, should signalise the year of his retirement from the post of R,esidenc\r Surgeon at Hyderabad by the publication of a volume on Chloroform, a subject with which he has been identified for many years past, and in defence of his views on which, and those of his master Syme, he has fought non sine gloria for many }7ears. The introduction to...

Rhabdomyolysis and thinner intoxication

 Abstract We report a case of paint thinner intoxication by inhalation, with rhabdomyolysis, renal failure, skin lesions and severe sciatic nerve lesion at gluteal region.

Chloroform